Broad Area Colloquium For AI-Geometry-Graphics-Robotics-Vision

Simulation-Based Medical Planning for Cardiovascular Disease

Charles A. Taylor
Assistant Professor of Research
Department of Surgery
Department of Mechanical Engineering
School of Engineering (by courtesy)
Stanford University

Wednesday, January 26, 2000
refreshments 4:05PM, talk begins 4:15PM
TCseq201, Lecture Hall B


The current paradigm for surgery planning for the treatment of cardiovascular disease relies exclusively on diagnostic imaging data to define the present state of the patient, empirical data to evaluate the efficacy of prior treatments for similar patients, and the judgement of the surgeon to decide on a preferred treatment. The individual variability and inherent complexity of human biological systems is such that diagnostic imaging and empirical data alone are insufficient to predict the outcome of a given treatment for an individual patient. We have proposed a new paradigm of predictive medicine in which the physician utilizes computational tools to construct and evaluate a combined anatomic/physiologic model to predict the outcome of alternative treatment plans for an individual patient. We are implementing the predictive medicine paradigm in software systems developed for Simulation-Based Medical Planning. These systems provide an integrated set of tools to test hypotheses regarding the effect of alternate treatment plans on blood flow in the cardiovascular system of an individual patient. They combine internet-based user interfaces developed using Java and VRML, image segmentation, geometric solid modeling, automatic finite element mesh generation, computational fluid dynamics and scientific visualization techniques. Progress in developing and validating these methods will be presented in addition to broader issues related to applying computer simulation methods in biomedical engineering and sciences.

About the Speaker

Professor Taylor received his B.S. degree in Mechanical Engineering in 1987 from Rensselaer Polytechnic Institute. He then joined the Engineering Physics Laboratory at GE Research & Development Center in Schenectady, New York where he worked on projects ranging from polymer process modeling to aircraft engine design. He received his M.S. degree in Mechanical Engineering in 1991 and his M.S. Degree in Mathematics in 1992 from Rensselaer Polytechnic Institute. He entered the Ph.D. program in the Division of Applied Mechanics at Stanford in 1992 and earned his Ph.D. degree in 1996 for his work on finite element modeling of blood flow. He was co-advised by Professor Tom Hughes and Professor Chris Zarins, Chief of Vascular Surgery at Stanford. Dr. Taylor joined the faculty in 1997 as an Assistant Professor (Research) in the Department of Surgery and holds a courtesy appointment in the Department of Mechanical Engineering. He founded and currently directs the Stanford Cardiovascular Biomechanics Laboratory and is particularly interested in the application of computational and advanced imaging methods to the study of the cardiovascular system. He is internationally recognized for the development of simulation-based surgery planning methods.
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Last modified: Fri Jan 7 11:23:04 PST 2000